Tuesday, August 25, 2020

Essay --

Iran, India, and Mexico are in incredibly various pieces of the world, making them altogether different from one another. The three nations have various narratives, geologies, and normal assets that have molded their turn of events. All things considered, an investigation of Iran’s, India’s, and Mexico’s monetary turn of events and globalization, media access and inclusion, and political pioneers, shows that there are some unquestionable likenesses. Regardless of the three nations being comparative somehow or another, general Iran, India, and Mexico are incredibly unique in relation to one another; every nation has an alternate authentic foundation that has molded it to be what it is today financially, socially, and strategically. I. Economic Development and Globalization Iran: In Iran, the economy depends on oil for a great part of the government’s income. Generally speaking in Iran, the state has an inadequate state area, with statist strategies that control quite a bit of what is financial arrangement. This makes a great deal of monetary issues, causing Iran’s economy to depend on oil. There isn't a very remarkable private segment in Iran other than little workshops, cultivating, and some assembling. The government’s value controls and appropriations frequently upset private division development. In Iran, there is a decent measure of casual monetary trade outside of government guideline, just as debasement. In the mid 1990’s Iran’s government acknowledged they expected to improve numerous components of the economy. One significant law made to improve the economy was President Mahmud Ahmadi-Nejad’s Targeted Subsidies Law. The Majles, Iran’s national administrative body, passed this law in 2010 to lessen state appropriations on food and vitality. Over a time of five years, Iran’s governing bodies attempted to expel appropriations from the economy that were very ... ... be said for Iran and India. Mr. Singh, in the same way as other of the political world class in Mexico, is exceptionally instructed. In spite of the fact that Iran, India, and Mexico are comparable somehow or another monetarily, socially, and strategically, generally they are altogether different. Iran’s economy depends on oil, while India’s economy is more administrations arranged. All things considered, Mexico’s economy is like India’sâ€both having noteworthy private segments. Additionally, Iran, India, and Mexico are comparable in that every nation has a state-run TV broadcasting. Notwithstanding, Iran’s government is obviously the most severe with what its residents can view and Mexico is less exacting and has all the more communicating organizations. Iran is likewise not the same as India and Mexico since Iran has a religious ruler, Ayatollah Ali Khamenei, while the other two nations don't. By and large, these nations are totally different from one another.

Saturday, August 22, 2020

The Global Pharmaceutical Industry Case Study Example | Topics and Well Written Essays - 1500 words

The Global Pharmaceutical Industry - Case Study Example The worldwide pharmaceutical industry is very strange and in different geographic markets there happens to just a single incredible purchaser, for example the legislature. During the 80s and 90s the legislatures round the globe began to focus on the pharmaceuticals as an obvious objective so as to control the consumptions identified with medicinal services and get more noteworthy incentive for cash. These composed of exercises by the administrations is only an impression of the social contrasts. The business in obvious sense has worldwide and subsequently the work and proprietorship has gotten packed in not very many nations. Controllers have regularly been tested to diminish the overburdening of the developing zones identified with the region of biotechnology research.â There are likewise expanding pressure from bury nation valuing imbalance just as equal exchange. One such model would the distinction among USA and Canada (Henry, 2008, p. 89).Economic ForcesPatients as a rule have had next to no impact on the decision of cost and items, on the grounds that the specialists make the solution. Again the clinical professionals will in general kindness marked items. Then again the motivating forces to purchase items got diminished as the expenses were repaid or accepted by the back up plans or the heath care specialists. The flexibly of the pharmaceutical market is still very divided as not many organizations are holding a portion of over 11%-20%. The business has the nearness of some solid global player’s bases in France, Japan and India as Ranbaxy.... One such model would the contrast among USA and Canada (Henry, 2008, p. 89). Monetary Forces Patients as a rule have had next to no impact on the decision of cost and items, in light of the fact that the specialists make the solution. Again the clinical specialists will in general kindness marked items. Then again the impetuses to purchase items got diminished as the expenses were repaid or expected by the back up plans or the heath care specialists. The flexibly of the pharmaceutical market is still very divided as not many organizations are holding a portion of over 11%-20%. The business has the nearness of some solid global player’s bases in France, Japan and India as Ranbaxy. Notwithstanding, the ongoing monetary down turn has implied that the organizations needed to diminish the spending on R&D and subsequently number of new items that should arrive at the market has fallen (Churchill, 2009, p.211). Social Forces The time of increased birth rates age is moving toward retirement and there have been new endeavors with respect to the organizations to fill the need of treatment of the older. The end clients are presently much better educated about the items. The ascent of the web has helped the clients to get important data about drug store based items without any problem. Customers have become a great deal instructed and accordingly much all the more requesting (Brown, 2009, p. 209). Mechanical Forces Technological elements can really bring down the market passage hindrances and lessen the proficient creation levels and impact the re-appropriating choices. A portion of the components incorporate the R&D exercises, pace of innovation change and innovation motivating forces. One of the significant ramifications of the mechanical advancement has been the improvement of medications that can help

Saturday, August 1, 2020

Adequate

Adequate You are inadequate. At least that’s what advertisers would like you to believe. You bear witness to proof of your inadequacy every day: you see it on your TV, hear it on your radio, stare back at it on your computer screen and on highway billboards. There are plenty of messages all around you to reinforce your utter inadequacy. If you’re a male, you’re not a real man unless you drink this brand of beer and eat this particular cut of meat and drive this brand of sport utility vehicle. And if you’re a female, you’re not a real woman unless you squeeze into this size dress and don this shiny piece of jewelry and tote this purse with all the ostentatious C’s or LV’s on its leather exterior. Then, and only then, will you feel adequateâ€"or so they’d have you believe. But when you obtain these things, what happens? Do you feel long-term adequacy? No, of course not. Your thirst for over-indulgent consumption isn’t quenched when you obtain more material possessionsâ€"it’s just the opposite: your desire to consume increases; you’ve set the bar higher, and thus the threshold for future satisfaction is higher. It’s a vicious cycle. Consumption is an unquenchable thirst. You create that thirst, you manufacture the desire to consume more. Advertisers play their role, they help activate the desire you create, but ultimately the desire is yours to control. Once you realize you have control, you can break the cycleâ€"you can avoid the continuous downward spiral. There is one way out of consumption’s spiral: we must realize the things we purchase do not define who we areâ€"unless we allow them to. If we are defined by our things, we will never be happyâ€"but if we are defined by our actions, then we’ll have the opportunity to feel fulfilled by our everyday growth, we’ll have the opportunity to feel satisfied with our everyday contribution to others, and we’ll have the opportunity to be content every day of our lives. The stuff doesn’t make you happyâ€"you make you happy. Read this essay and 150 others in our new book, Essential.

Friday, May 22, 2020

Parliament Criminal Court - Free Essay Example

Sample details Pages: 6 Words: 1801 Downloads: 6 Date added: 2017/06/26 Category Law Essay Type Case study Did you like this example? Contemporary Issue The 2007 criminal case of R Vs Niehus, criticism of a District Court Judge Marie Shaw by State Upper House Member of Parliament Dennis Hood. Question Is Judicial Independence jeopardised by State Members of Parliament who publicly criticise the sentencing handed by Criminal Court Judges? Judicial Independence is crucial to the operation of a democratic society, leaving little debate that an independent judiciary is the â€Å"fragile bastion† in our democratic system of government. Thus judges, when presiding over cases, are entirely free from any intrusion or intimidation executed by external forces. The Westminster System, implemented from Britain, ensures the courts have the confidence of the community and all cases provide an outcome exclusively on merit, as Michael OConnell, Victims of Crime Commissioner (Appendix 3) states: â€Å"The Judiciary shall decide matters due to impartiality on the basis of facts.† However, questions have been raised whether judicial independence is jeopardised by external forces publicly criticising a judges verdict. One such example occurred when State Upper House Member of Parliament, Dennis Hood, publicly attacked District court Judge Marie Shaws final ruling in the 2007 criminal case of R Vs Niehus, prompting an order for her dismissal. David Swain, Retired Chief Magistrate (Appendix 2) reports, â€Å"Judicial Independence is a vital part of the Westminster System.† To guarantee absolute judicial independence and uphold the confidence of the community, the judiciary must have complete separation from both the Legislative and Executive arms of Government, and any other external political forces. Accomplishment of this is achieved in a number of ways; first, Judges are appointed by the Executive arm and dismissed by the Legislative arm, to avert the chance of one arm of Government grasping complete control over the judiciary and Section 72 of â€Å"The Australian Constitution Act† (1900) specifies the dismissal of a judge can only occur on two grounds; misbehaviour and incapacity. Secondly, a permanent tenure is provided, on the g rounds a judge must retire at the age of 70, with the exception of Family Court Justices, who have an obligation to retire at 65. This assures judges cannot be removed if their decision does not support the governments request, as Peter Hasket, Retired Magistrate (Appendix 4) states, â€Å"Even if a number of people dont want them, their position stays the same.† Thirdly, a fixed remuneration is guaranteed, preventing both salaries from being diminished throughout tenure and manipulation occurring. However, salaries can be increased by government on objective factors. Fourthly, judges are ensured judicial privilege, allowing them to have freedom of speech while presiding on the bench and delivering verdicts. Thus judges cannot be threatened by criminal prosecution or sued for vilification, a fact David Swain (Appendix 2) suggested â€Å"one can take comfort in.† Finally, individuals who are selected for judicial office must have suitable training and credentials in the law, and no discrimination is to occur on the basis of sex, colour, race, status, religion or political influence. The Honourable Justice John Basten- Judge of the Supreme Court New South Wales (2005:1) reports, â€Å"Principles of open justice play an important part of our courts.† Justice is governed in an open court, where the public has complete access, although exceptions occur, for example, courtrooms can only provide for a small number of spectators. Furthermore, for those who do not attend, sentencing remarks are available via the Internet, and significant cases are usually covered in the print and electronic media. This then ensures openness, as it is vital in promoting the publics confidence. However, information handed to the public via the media raises questions to the extent of its reliability. David Swain (Appendix 2) reports, â€Å"99% of all cases, which go through the courts dont get any media attention.† This indicates that the media has one priority, which is to attract public attention and have general appeal, in order to sell papers. As well as this, The Honourable Justice John Basten (2005:1) states, â€Å"reporters who cover trials often move from one court room to another during the course of a day, obtaining only an incomplete picture of what is happening in any particular case.† Along with media attention, public criticism is also created. â€Å"Sentencing reflects the views of the community, because in effect, they are prescribing parliaments will,† states Michael OConnell (Appendix 3). However, it is impossible to please all citizens, thus generating criticism of certain cases, usually through the media. A recent significant case, which generated much public criticism and uproar, was the 2007 criminal case of R Vs Niehus, ruled by District Court Judge Marie Shaw. Dennis Hood, publicly attacked her final ruling, and called for her removal due to the leniency of her suspended sentence. Dennis H ood (2007:1) questioned, â€Å"What possible reason can there be to allow Judge Shaw to continue to hear cases and hand down grossly inadequate sentences to hardened criminals?† Christopher Michael Niehus received a three-year suspended jail sentence, upon the condition that he entered a bond of $400 to uphold good behaviour for a two year period and perform 150 hours of community service, in respect of four counts of unlawful sexual intercourse. Marie Shaw (2007:3) states, â€Å"the matters which favour suspension to which your counsel has referred, are that you are a person of previous good character, you are someone who, both before these offences and subsequently, has engaged in age appropriate relationships. In my view, you are unlikely to offend again.† Marie Shaws position as District Court Judge, entitles her to consider all facts and circumstances and provide an outcome exclusively on merit, which she has confidently done. However, Dennis Hood completely disagreed with Marie Shaws suspended sentence, complaining to the media that, â€Å"abusing a young girl, a 14-year-old girl† resulted in â€Å"a sentence of 150 hours of community service.† Denis Hoods actions of publicly calling for Marie Shaw to be dismissed raised the question to the extent of criticism, which should be allowed without the risk of jeopardising Judicial Independence. David Swain (Appendix 2) states, â€Å"Every now and again one or two people, particularly politicians, turn to their favour, and politically ‘go too far, which can arguably be an attack on independence.† Beneficial criticism of the Judiciary is welcomed and appropriate as it allows public scrutiny and maintains the confidence of the community through integrity. As well as this freedom of speech in our democracy is a fundamental right. Nevertheless, as Michael OConnell (Appendix 3) states, â€Å"the criticism, as in any situation, should focus on the issue, not the ind ividual,† Denis Hoods public ‘out-burst, was directly aimed at Judge Marie Shaw, ultimately causing considerable distress and embarrassment, Marie Shaw (2007:1) states,† I was bitterly disappointed that he attacked my fitness for office on the basis of inaccurate statements.† Soon after Dennis Hoods public ‘outburst, leading judges raised alarms that Judicial Independence was under fire. Chief Justice John Doyle and Chief Judge Terry Worthington stated, â€Å"Mr Hoods push for her removal is contrary to constitutional principle and threatens to undermine the judiciarys independence, also that any attempt to remove a judge could lead to inappropriate pressure on judges to operate in a way acceptable to politicians and any threat to remove a judge from office because of criticism of a judges decision sets a dangerous precedent and who will be threatened next?† Despite maintaining the integrity of its independence, the judiciary understands it will never be immune from public criticism, as it is an essential component of our democratic system of government. David Swain (Appendix 2) states, â€Å"The judiciary is in the same position as any other public institution. It must expect, and should be prepared to deal with, criticism.† However, reforms need to be made in Marie Shaws case, where public criticism was undoubtedly incorrect and taken to a level, which may have jeopardised her independence. Any public criticism, of any arm of government, should always be of benefit to that arm of government. The criticism must purely be aimed at the issues involved and never a direct attack on an individual. In regards to certain views of ‘soft sentences, by politicians as such, the official method of parliamentary review should be employed, not via media outlets. As well as this Michael OConnell (Appendix 3) states, â€Å"(I) rely on victims views. In general, victims who contact me feel that the sentence imposed w as too lenient- in other words, they expected a harsher sentence.† I am confident that the question posed: ‘Is Judicial Independence jeopardised by State Members of Parliament who publicly criticise the sentencing handed by criminal court judges? can be answered in the negative. Dennis Hoods public ‘outburst, was certainly demoralising for Her Honour Judge Shaw, which moved Hood to apologise and retract his statements. Dennis Hood stated in his public apology, â€Å"I recognise that by making these assertions I have caused considerable distress and embarrassment to Judge Shaw.† Although the criticism was unjust, Michael OConnell (Appendix 3) reports, â€Å"it will not affect the general sentencing practices.† Our Attorney-General often comments that, â€Å"courts in common law countries have been independent of the Parliament since the 1600s.† Our current sentencing system works effectively in Australia.   There should be no need to mak e any reforms to the current system as any changes may in fact place the communitys trust in the overall system  at risk.   Our current judicial practices must be preserved to ensure that judges and the overall judicial system are preserved and the so called â€Å"Fragile Bastion† is at all times protected. Judges are accountable for their overall actions and the decisions that they make.   The issue is that parliamentarians need to be careful that when criticising judges it is done lawfully.   As it was clearly stated by David Swain (Appendix 2), The sentencing process is conducted in a manner that does reflect the values, morals and concerns of the community. We need to trust in our current structures of being able to maintain Judicial Independence and preserve the communitys confidence in the legal system. Don’t waste time! Our writers will create an original "Parliament Criminal Court" essay for you Create order Bibliography 22/11/2007, ‘Remove judge, urges Upper House MP, ABC News, viewed 24/04/2008 https://www.abc.net.au/news/stories/2007/11/22/2098109.htm Bailey, Geoff, ‘Legal Studies Key Ideas Stage 2, Adelaide, 2006 Bash, Barbara, ‘Legal Studies Essentials SACE 2, Adelaide Tuition Centre 2008 Basten, John 2005, ‘Court and Media Relationships, viewed 26th April 2008, https://www.lawlink.nsw.gov.au/lawlink/Supreme_Court/11_sc.nsf/pages/SCO_basten301005 Dowdell, Andrew, Henderson, Nick, 23/11/2007, ‘Attorney-General, rejected calls to sack District Court Judge, ABC News, viewed 23/04/2008 https://www.news.com.au/adelaidenow/story/0,22606,22803291-5006301,00.html Doyle, John, 22/08/2003, ‘Judicial Independence and the Separation of Powers, viewed 15/05/2008, https://netk.net.au/SA/SA16.asp#TopOfPage Hasket, Peter, 13/05/2008, Notes from interview Hood, Denis, 05/05/2008, Notes from interview ‘Judicial Sentencing, 22nd November 2007, Extract from the Legislative Council Hansard, viewed 10th May 2008 OConnell, Michael, 08/05/2008, Notes from interview Shaw, Marie, ‘R v Christopher Michael Niehus Sentencing Remarks, District Court, Adelaide, 2007 Swain, David, 06/05/2008, Notes from interview Swain, David, ‘Are Judges Truly Independent?, viewed 6th May 2008 Swain, David, ‘Do Sentencing Laws Reflect Community Attitudes and Values, viewed 6th May 2008

Sunday, May 10, 2020

Profile of Serial Killer William Bonin, The Freeway Killer

William Bonin was a serial killer suspected of sexually assaulting, torturing and killing at least 21 boys and young men in Los Angeles and Orange County, California. The press nicknamed him the  The Freeway Killer, because he would pick up young boys who were hitchhiking, sexually assault and murder them, then dispose of their bodies along the freeways. Unlike many serial killers, Bonin had multiple accomplices during his murder spree. Known accomplices included  Vernon Robert Butts, Gregory Matthew Miley, William Ray Pugh, and James Michael Munro. In May 1980,  Pugh was arrested for stealing cars and while in prison provided detectives details connecting the freeway murders to William Bonin in exchange for a lighter sentence. Pugh told detectives that he accepted a ride from Bonin who bragged that he was the Freeway Killer. Later evidence proved that Pugh and Bonins relationship went beyond a one-time ride and that Pugh participated in at least two of the murders. After being placed under police surveillance for nine days,  Bonin was arrested while in the process of sexually assaulting a 15-year-old boy in the back of his van. Unfortunately, even while under surveillance, Bonin was able to commit one more murder before his arrest. Childhood - Teen Years Born in Connecticut on January 8, 1947, Bonin was the middle child of three brothers. He  grew up in a dysfunctional family with an alcoholic father and a grandfather who was a convicted child molester. Early on he was a troubled kid and ran away from home when he was eight years old. He was later sent to a juvenile detention center for various small crimes, where he allegedly was sexually molested by older teens. After leaving the center he began molesting children. After high school, Bonin joined the U.S. Air Force and served in the Vietnam War as a gunner. When he returned home, he married, divorced and moved to California. A Vow to Never Get Caught Again He was first arrested at age 22 for sexually assaulting young boys and spent five years in jail. After his release, he molested a 14-year-old boy and was returned to prison for an additional four years. Vowing never to get caught again, he began killing his young victims. From 1979 until his arrest in June 1980, Bonin, along with his accomplices, went on a raping, torturing  and killing spree, often cruising California highways and streets for young male hitchhikers and school children. After his arrest, he confessed to killing 21 young boys and young men. Police suspected him in 15 additional murders. Charged with 14 of the 21 killings, Bonin was found guilty and sentenced to death. On February 23, 1996, Bonin was executed by lethal injection, making him the first person to be executed by lethal injection in California history. Freeway Killer Victims Thomas Lundgren, age 14, murdered on May 28, 1979. Accomplices Vernon Butts and William PughMark Shelton, age 17, murdered on August 4, 1979Marcus Grabs, age 17, murdered on August 5, 1979. Accomplice Vernon ButtsDonald Hayden, age 15, murdered on August 27, 1979. Accomplice Vernon ButtsDavid Murillo, age 17, murdered on September 9, 1979. Accomplice Vernon ButtsRobert Wirostek, age 16, murdered on September 27, 1979John Doe, age 14-20, murdered on November 30, 1979Dennis Frank Fox, age 17, murdered on December 2, 1979. Accomplice James MunroJohn Doe, age 15-20, murdered on December 13, 1979Michael McDonald, age 16, murdered on January 1, 1980Charles Miranda, age 14, murdered on February 3, 1980. Accomplice Gregory MileyJames McCabe, age 12, murdered on February 3, 1980. Accomplice Gregory MileyRonald Gaitlin, age 18, murdered on March 14, 1980Harry Todd Turner, age 15, murdered on March 20, 1980. Accomplice William PughGlen Barker, age 14, murdered on March 21, 1980Russell Rugh, age 15, murdered on March 22, 1980Steven Wood, age 16, murdered on April 10, 1980Lawrence Sharp, age 18, murdered on April 10, 1980Darin Lee Kendrick, age 19, murdered on April 29, 1980. Accomplice Vernon ButtsSean King, age 14, murdered on May 19, 1980. Confessed accomplice William PughSteven Wells, age 18, murdered on June 2, 1980. Accomplices Vernon Butts and James Munro Co-Defendants: Vernon Butts: Butts was 22 years old and a factory worker and part-time magician when he met Bonin and began participating in raping and murdering at least six boys. He hung himself while awaiting trial.Gregory Miley: Miley was 19 years old when he got involved with Bonin. He pled guilty to participating in one murder for which he received a sentence of 25 years to life. He is currently in prison.James Munro: Bonin was Munros boss and landlord when Munro participated in the murders of two boys. In a plea bargain, he pled guilty to one murder and received a sentence of 15 years to life. He is still in prison but trying to appeal claiming he was tricked into a plea bargain.William (Billy) Pugh: was the most active accomplice who was charged with one murder, although he confessed to killing two victims. He received  six years for voluntary manslaughter in a plea bargain. Arrest, Conviction, Execution After William Bonins arrest, he confessed to killing 21 young boys and young men. Police suspected him in  an additional 15 other murders. Charged with 14 of the 21 killings, Bonin was found guilty and sentenced to death. On February 23, 1996, Bonin was  executed by lethal injection, making him the first person to be executed by lethal injection in California history. During Bonins murder spree, there was another active serial killer by the name of Patrick Kearney,  using the California freeways as his hunting ground.

Wednesday, May 6, 2020

What Does Democracy Signifies Free Essays

If firms were not in a competitive environment, they would be able to control the market. Still, there are other factors, which stop firms from controlling the market. Namely the fact that firms do not have perfect information, issues about its objectives or firms may not even know how to maximise profits. We will write a custom essay sample on What Does Democracy Signifies or any similar topic only for you Order Now This is due to the fact that companies use different pieces of information or interpret it differently. Firms can use different tasks in order to achieve the same aim. Companies often set themselves in mission statement; or they try to set goals by which the statement will be achieved; or a specific objective. A firm aims to maximise profits, and that is what this essay will focus on. First, it will give a brief definition of firm and define its objectives. Second, it will examine the assumption of profit maximisation. Third it will confirm whether firms really maximise their profits. Then it will follow by mentioning other alternatives to profit maximisation. Finally in the conclusion, it will include the results of this essay. It is understood by firm ‘ an organisation consisting of one or more individuals working as a decision-making unit to produce goods or services† (Atkinson, B. R. Miller â€Å"Business Economics†). The firm†s objectives are to maximise profits. The amount that the company receives for the sale of its output is called its total revenue. The amount that the firm pays to buy inputs is called its total cost. We, then, define profit as a firm†s total revenue minus its total cost. Thus, if a firm gets  £10,000 from selling its output and spends  £90,000 producing this output, its profit is  £10,000. The above diagram shows how costs, revenue and profit interact with each other. Costs go up with output as well as revenue, but just till a certain point. Revenue falls due to the firm†s necessity to lower its costs in order to rise selling. In other words, in the cost curve firms will experience increasing returns, followed by decreased returns. Revenue will rise, as price falls and quantity goes up. Profits will occur between the two points were the curves intersect. The slope of the two curves are the same and they are given by the marginal value (marginal revenue and marginal cost). Hence, to maximise profit, marginal revenue must equals marginal cost. In order to achieve this, firms must have all the details on the demanded product. Profit maximisation plays an important role within a firm, as it makes innovation possible as well as the payment of higher wages and greater job offers. Moreover, profits create incentives as it is rewarding for entrepreneurs, whose time and skills contributed to the firm†s success. Increasing profits leads to a rise in output and with it consumers also get more satisfied. Thus, it can be said that it is also beneficial to society to raise profits. Profits provide a source of revenue, which reverts in favour of new factories and machinery. In addition, profits encourage innovation again society benefits from it. However, there are still motives for companies to refuse to have high levels of profit. Companies will just be able to maximise profits if owners are in control of the firms. However, in big companies such as Coca-Cola or Shell where, probably, there are many shareholders, it is more difficult to maximise profits. As, in this case managers are more likely to run the business. This leads us to do so called ‘principal-agent problem†. Where owners† objectives may be different from the managers. Hence, due to the rise of the joint-stock company there has developed a split between ownership and control. Ownership belongs now to shareholders, while managers exerce the power of controling. Still, there are motives to choose to maximise profits. Firstly, profit maximisation is still a sign of power, so in a competitive environment firms will opt to maximise profit to ensure its survival; Secondly, both the principal and agent, when confroting a situation of no option, they would prefer to maximise profits rather than lower them; Most important, due to profit maximisation it became possible for economists to study the output and the price of companies and, consequently, study the market. In analysing the managerial approach, it can be noticed that managers will then aim to take precedents over the objectives of the owner. In this case the primary goal of a firm is to maximise its revenue. This will occur because managers† remuneration is more likely to be linked to revenue than to profitability. For example, bank†s tend to regard growing sales positive as well as financial markets, who likes to see growing sales revenue. Most important, sales revenue is still seen as an indication of success. The same occurs to firms that have their main aim to maximise growth. Just like raising revenue, raising growth also leads to higher bonuses. Managers also benefit from it because their status gets better, as the firm has more prestige. Such theory, also suggests that managers try to maximise their own profit benefits. In other words, use firms to get their objectives. Still, there is other theory that states that managers in fact do not maximise anything at all, but they attend to satisfactory levels, theory developed by H. Simon. Here, managers will set a minimum level of profit, keeping shareholders satisfied. This type of approach is probably used by small firms, which are not able to take the big risks that profit maximisation can lead to. Moreover, managers try to keep all members of the firm satisfied, so profit maximisation becames a hard task to achieve. In general, conditions of uncertainty difficults the achievement of sales and profit maximisation. In practise management tries to obtain growth in output and assets from one year to the next and achieve satisfactory growth. On one hand, it is true to say that there is a separation of ownership and control, consequently, this stresses the importance of managers. On the other hand, it is difficult to describe how the different objectives of management and shareholders interact to produce the goals and objectives of the company. How to cite What Does Democracy Signifies, Papers

Thursday, April 30, 2020

The House of Seven Gables Essay Example

The House of Seven Gables Essay Nathaniel Hawthorne’s The House of Seven Gables focuses on the Pyncheon family cursed by the cruelty of one of its members to the family of Matthew Maule decades before. Like the biblical Ahab, the old aristocratic Pyncheon wrests a beautiful piece of land from his much poorer fellow man Maule, and on it he builds his seven-gabled house. Now, decades later, the house is occupied by his relative Hepzibah, her lodger Holgrave Maule, and eventually by her formerly imprisoned brother Clifford. The three characters play very important roles in the novel, both literally and symbolically, and their presence contributes greatly to the significance of the work as a whole. In Hepzibah can be seen the symbolic representation of the evils of the father being visited upon the children for generations. She is an old maid, and in her life so far is reflected the barrenness and non-productivity that such a curse (as was placed upon the family by the old Matthew Maule) generates. Though unmarried and without children, she seemed to have subscribed to the creeds of Cult of Domesticity (or the Cult of True Womanhood), and was now forced to desecrate herself by violating that cult’s forbidding women to do business. Of Hepzibah’s entrance into trade, Hawthorne writes, â€Å"It was the final throe of what called itself old gentility. A lady—who had fed herself from childhood with the shadowy food of aristocratic reminiscences, and whose religion it was that a lady’s hand soils itself irremediably by doing aught for bread—this born lady, after sixty years of narrowing means is fain to step down from her pedestal of imaginary rank † (35). This points not just to the relic of aristocracy from which Hepzibah has sprung, but also to the irony of the creeds of the Cult of Domesticity, which demands that a woman be sexually frigid (apparently like Hepzibah), and at the same time fertile. The incongruence of the two possibilities places Hepzibah in a bind, because her frigidity has led her toward spinsterhood and with no way to stay alive but to soil her hands, which she is also forbidden to do according to her aristocratic pride. We will write a custom essay sample on The House of Seven Gables specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on The House of Seven Gables specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on The House of Seven Gables specifically for you FOR ONLY $16.38 $13.9/page Hire Writer In any case, she condescends to open a cent shop, transforming herself from â€Å"the patrician lady [†¦] into the plebeian woman† (35). The shop undergoes a similar transformation, but with the opposite effect. The shop, which was once in a state of neglect, is now polished and painted and made fruitful with stocks placed on its shelves. This shop may, in fact, be symbolic of Hepzibah’s true progress, which is not the one of devolution as she thinks. Rather, she has stepped up from the disgrace and poverty of unemployment and near-mendicancy to the fruitfulness and independence of trade. Hepzibah’s brother, Clifford, is ruined in jail, sent there to be punished for a crime he did not commit, and wastes thirty years of his life. He returns the mere shell of a man. In reality, he is still a child, having lost his opportunity to grow up and to deal with the everyday situations of manhood. The cold severity of the prison walls have so impressed darkness upon him that he can find no force in himself that propels him to be nice to the sister who has sacrificed her dignity for him. Clifford’s exposure to the drab and dreary prison has intensified his love for beauty. Yet he demonstrates superficiality in his inability to perceive beauty in his sister, who has grown harsher in her appearance not just because of her age but also because of her distress for his imprisoned condition over the years. That she is scorned by him, Hawthorne describes as â€Å"the mournfullest of pities† (137), and it is indeed, showing that Clifford’s sensibilities where beauty is concerned are as retarded as his manhood. He exhibits again the characteristics of a child who has not yet gained the aesthetic sophistication that allows people to see beauty beyond the merely merry and colorful. Holgrave Maule is Hepzibah’s boarder and, unbeknownst to her, the descendant of Matthew Maule who allegedly placed a curse on the family. Holgrave is there under false pretences, yet he proves himself to be the most sympathetic of the characters. He has accomplished much in his short life, distinguishing himself in many offices, and now he befriends Phoebe Pyncheon (Hepzibah’s niece), becoming â€Å"the only youthful mind with which Phoebe had an opportunity of frequent intercourse† (179). Though he has reason to dislike the Pyncheons, his deep-seated good nature causes him inevitably to behave favorably toward them all. His good nature causes him to refrain from alerting the police about Judge Pyncheon’s death when he knows that the circumstantial evidence would immediately implicate Clifford and Hepzibah. He proves himself to transcend the malice of the curse in his attitude here, and also in his refusal to manipulate Phoebe though he succeeds in hypnoti sing her. He is in truth a character of sympathy to whom we must â€Å"concede [†¦] the rare and high quality of reverence for another’s individuality† (218). The three characters Hepzibah, Clifford and Holgrave represent the various dimensions of the story. Hepzibah points toward the socially critical aspect of the text as she represents the relics of a dying aristocracy. In her appearance and her behavior, she exhibits the characteristics of one who has fallen from grace, and one who has disregarded her own humanity in adherence to the creeds of a cult. The victimized Clifford has too lost his bloom, and has not gained in return the seasoned experience of life, but a retarded growth that offers nothing but the most puerile response to beauty. Holgrave’s character demonstrates a redemptive idea. He is the one who has reason to hate, yet he redeems his clan (and, by extension, humanity), showing himself to be a man of honor in his dealings with the family of the man who ruined his own.

Friday, March 20, 2020

Underlying assumptions of intelligence tests Essays

Underlying assumptions of intelligence tests Essays Underlying assumptions of intelligence tests Essay Underlying assumptions of intelligence tests Essay How can intelligence be tested? Critically evaluate the underlying assumptions of intelligence tests. Intelligence is a very controversial. It is seen as an obsession in daily life and focuses on certain types of intelligence. Francis Galton was the first person to design a mental test. Galton believed that an individuals mental ability could be determined through the deviation of their performance on a simple test to the mean. He believed that the greater a persons sensory perception the more intelligence they had. However, Galton never produced a theory about intelligence testing, but paved the way for other psychologists to produce theories and tests.Spearmans (1904) theory suggested that intelligence was an innate, inherited quality. He suggested that there were two main factors that determined a persons intelligence; these were general intelligence, needed to perform all tasks and specific intelligence, which is needed to perform specific tasks .i.e., most people can drink out of some sort of cup, this needs general intelligence, however, not all people can sing in tune, this is specific intelligence.Alfred Binet and Theodore Simon (Simon and Binet, 1905) produced the first form of modern intelligence testing in 1905. The test had a practical purpose and was used to identify children who may need extra help with their school work. Due to the purpose of the test, the exercises Binet and Simon asked the children to complete were very similar to tasks the children completed within schools, i.e. measures of vocabulary, comprehension of facts and relationships and mathematical and verbal reasoning.The Binet Simon test was later modified and extended by Lewis Terman and his associates at Stanford University where it was translated for use in the United States (Terman 1916, Terman and Merrill, 1937). The test became known as the Stanford-Binet test and is still being used referred to as Intelligence Quotient; (I.Q). the I.Q. score was calculated by comparing the childs chronological age, (which means their age is years and months), with their mental age (which refers to the childs ability to solve problems of certain levels.) i.e if a child could answer questions designed for 8 year olds, but not them designed for 9 year olds, the child would have a mental age of 8.The I.Q test that is now most commonly used is know n as the Wechsler Intelligence Scales for children, or the WISC. The most frequently used test used by psychologists is the third revision of the Wechsler Intelligence Scales known as the WISC-III. David Wechsler originally developed the test, which was series of ten different problems that ranged from very easy to extremely difficult; these ten problems were also divided into two subgroups.The verbal scale that involved tasks measuring vocabulary, understanding of similarities between objects and general knowledge. The other subgroup was the performance scale, which involved non-verbal tasks such as arranging pictures in to orders, or copying patterns using coloured blocks. Many psychologists find that this definition of verbal and non-verbal tasks helpful as different between the two skills can identify particular kinds of learning difficulties, i.e. dyslexia.However, ever since the I.Q tests were introduced there have been criticisms about them. Before 1937, the mean score of wom en using the Stanford-Binet test was on average ten points lower than the average score for men. Although at first it was generally suggested that this was because women were not as intelligent as men, it was later suggested that the questions were more directed towards male dominated areas of questioning than women, for example relating questions in terms of cars, card games, mechanics, etc. which at the time was made oriented. Therefore, it was decided to eliminate this discrepancy by modifying the questions to ensure that both males and females would archive around the same average score.According to Heather, (1976) this makes the test less efficient because there may be a natural difference between the intelligence levels of men and women through out different points of history, however, by using the new these differences may not be picked up. For example if the I.Q scores were not created to produce approximately the same scores for both males and females we may be able to see why females are currently doing better academically than males.Therefore, this could limit the efficiency of I.Q testing through either historically suggesting that women were inferior to men through their lower I.Q. scores, or through influencing the tests to create equal results for both males and females. It is difficult to say whether the tests were gender bias or whether the psychologists behind the changes to the tests did this to provide unbiased results through positive discrimination towards women.Another criticism of the I.Q. tests that there is an average 10-15 point difference between the White European average and the Afro- Caribbean average, (Brody, (1992) Fagan Singer (1983) Peoples, Fagan Drotar, 1995); (Neisser et al 1996) Heather, (1976) suggests that this difference can be reduced through changing the questions to suit a more mixed ethnic group of participants. However, it was suggested that this would affect the tests Predictive Validity. By changing the tests to reduce the racial differences, but without changing the social inequalities within our society would only create a more ineffective test. In order to reduce the ethnic I.Q. score difference, society must first change their attitudes towards other cultures, especially within education/ training and jobs.How ever, Jensen, (1969) published an article called How much can we boost I.Q. and schooling achievement? within which he made a controversial suggestion that Genetic factors are strongly implicated in the average negro-white intelligence differences. The preponderance of the evidence is, in my opinion, less consistent with a strictly environmental hypothesis than with a genetic hypothesisOther psychologists including Eysenck (1971) and Herrnstein (1971) agree with Jensn. Jensen suggests that 80% of the difference between blacks and whites is due to the blacks genetic inferiority and 20% due to environmental factors. However, Jensen does not have the biological evidence to back up his claim; he also used a bias sample to carry out his study that was a mainly white population.

Wednesday, March 4, 2020

The Coalescent Theory and Evolution

The Coalescent Theory and Evolution One part of the modern synthesis of evolutionary theory involves population biology and, on an even smaller level, population genetics. Since evolution is measured in units within populations and only populations can evolve and not individuals, then population biology and population genetics are intricate parts of the Theory of Evolution through Natural Selection. How the Coalescent Theory Affects the Theory of Evolution When Charles Darwin first published his ideas of evolution and natural selection, the field of Genetics had yet to be discovered. Since tracing alleles and genetics is a very important part of population biology and population genetics, Darwin did not fully cover those ideas in his books. Now, with more technology and knowledge under our belts, we can incorporate more population biology and population genetics into the Theory of Evolution. One way this is done is through the coalescence of alleles. Population biologists look at the gene pool and all available alleles within the population. They then try to trace the origin of these alleles back through time to see where they started. The alleles can be traced back through various lineages on a phylogenetic tree to see where they coalesce or come back together (an alternate way of looking at it is when the alleles branched off from one another). Traits always coalesce at a point called the most recent common ancestor. After the most recent common ancestor, the alleles separated and evolved into new traits and most likely the populations gave rise to new species. The Coalescent Theory, much like Hardy-Weinberg Equilibrium, has a few assumptions that eliminate changes in alleles through chance events. The Coalescent Theory assumes there is no random genetic flow or genetic drift of alleles into or out of the populations, natural selection is not working on the selected population over the given time period, and there is no recombination of alleles to form new or more complex alleles. If this holds true, then the most recent common ancestor can be found for two different lineages of similar species. If any of the above are in play, then there are several obstacles that have to be overcome before the most recent common ancestor can be pinpointed for those species. As technology and understanding of the Coalescent Theory become more readily available, the mathematical model that accompanies it has been tweaked. These changes to the mathematical model allow some of the previously inhibitive and complex issues with population biology and population genetics have been taken care of and all types of populations may then be used and examined using the theory.

Monday, February 17, 2020

MKT305 Coursework Example | Topics and Well Written Essays - 750 words

MKT305 - Coursework Example is improving the customer shopping experience since web-to-store transactions have eliminated the problems encountered in home delivery (Weinstein and Cahill 2014). Web-to-store has enabled the retailers to use their existing networks and group parcels thus increasing their sales volumes. According to marketing theory, target marketing requires market and customer segmentation and effective customer segments should be identifiable, accessible, measurable and reachable through the marketing and distribution channels (Egan 2007). The market should be sufficient and should have unique needs and thus ‘click and collect’ service of Marks and Spencer targets the online shoppers who have embraced e-commerce. The distinct customer characteristics include the life stage, the social-economic status, purchasing intensity and online involvement of the customers. Marks and Spencer targets young adults and techno-savvy consumers who have busy schedules that demand. The target customer segment includes the working professionals, students and middle-income customers who prefer shopping at the comfort of their homes. This customer segment often outsources the delivery to a third-party and do not have the control or opportunity to track the delivery of the orders to their homes (Hart 2003). The online shoppers believe that shopping is fun and explore a lot of information online before making a purchase decision. The customers have an appealing income and are techno-savvy since most of them get information from their internet enabled devices. The customers are enthusiastic and impulsive and tend to spend most of their income on entertainment, fashion, books and new personal devices due to their exciting lifestyles (Hart 2003). The customers are reflective and motivated by knowledge and thus compare different products before making the purchase decision. Another unique purchasing behaviour is the demand for stylish, functional and value for money and thus the customers prefer

Monday, February 3, 2020

Multi-Cultural and Political Society Essay Example | Topics and Well Written Essays - 2750 words - 2

Multi-Cultural and Political Society - Essay Example In a political society like America, several interest groups are present, which are based on religious, racial, economic, political, or occupational (Ogene 24). Each of these groups always tries to place their self-interest ahead of their national interest which has been a major issue addressed by various scholars in the American society. Madison’s dilemma is the conception with the American political system, a system where people are at liberty to express their opinions and are given the privilege to petition the government on certain issues (Rosenau 46). In such system, pursuance of self-interest ahead of national interest is visible. The pursuance of self-interest ahead of national interest has been the concern of major stakeholder in the American polity. With the major actors stuck in the middle of whether to subvert self-interest group. A situation that would likely undermine the freedom of speech and rights of the citizens which portends the rise of an autocratic government that will degenerate into the oppression of the masses, or either maintains the political freedom operating in the system as being recognized in the democratic tenets. Nevertheless, granting political freedom to American populace would expose the system to circumstances that could hinder the growth of the political system (Rosenau 39). Interest groups in a democratic society are the various groups that seek to influence governmental decisions in a way to favor their interest (Ogene 12). They also help in the articulation and aggregation of interest in a way to make the decision-making process less cumbersome for political office holders. In the United States of America, there are different ethnic groups that are present due to their multi-ethnic and interracial background. Freedom of expression as a fundamental principle in a democratic system, allows the public to voice their opinion on various governmental policies.

Sunday, January 26, 2020

Effect of Semecarpus Anacardium on Plasma Nitrates

Effect of Semecarpus Anacardium on Plasma Nitrates OBSERVATION AND RESULT 7. Observation and Result 7.1 Behavioral Parameters Values are expressed MEAN ±SEM, n = 6, ** = P Fig. 7.1 Effect of Semecarpus Anacardium on Behavioral Parameters on Stress Induced Anxiety in Mice. 7.2 Biochemical Estimation Values are expressed MEAN ±SEM, n = 6, ** = P Fig. 7.2 Effect of Semecarpus Anacardium on different Biochemical Parameters in Stress Induced Anxiety in Mice. Fig. 7.3 Effect of Semecarpus Anacardium on glutathione reductase activity in Stress Induced Anxiety in Mice. 8. Discussion Behavioral parameters are the primary evidence to confirm anxiety as well as anti-anxiety effect of treatments. All the parameters are based on pathophysiology of anxiety because anxiety or fear is evaluated through stress or immobilization of animal like mice and rats. Elevated Plus Maze (EPM) After immobilization of animals for 3hr, the drug treatment was started for all groups except negative control. Time spent in open arm and closed arm were observed. Time spent in open arm were significantly increased (P>0.001) after administration of Semecarpus anacardium at dose of 200 mg/kg 175 ±2.2046 sec. as compared with negative control (258 ±3.2018 sec.). In fear, animal is more favorable to dark area which was shows in negative control. Force Swim Test (FST) Time cycle in seconds was count in all groups. Time cycle per five minute were significantly increased (P>0.001) in Semecarpus anacardium at dose of 200 mg/kg (20 ±4.2044) compared with negative control (25 ±2.5421). Light and Dark Test After immobilization of animals for 3 hr, the drug treatment was started for all groups except negative control. Time spent in light and dark area was observed. Time spent in light area were significantly increased (P>0.001) after administration of Semecarpus anacardium at dose of 200mg/kg (178 ±3.5041 sec.) as compared with negative control (58 ±2.1245 sec.). In fear, animal is more favorable to dark area which was shows in negative control. Open Field Test (OFT) OFT is the test to evaluate anti- anxiety effect as well as to compare the statistics with actophotometer because each squire in OFT is 10 Ãâ€"10 cm and each electrode’s difference in actophotometer is 6 cm so the reading should be double in OFT. Animal in control group were shows significant walk fullness in OFT (45 ±2.2405 sec.). After administration of Semecarpus anacardium at dose of 200mg/kg, the animal was shows significant effect (P>0.001). Rearing is the parameter in OFT which shows alertness of animals. After administration of Semecarpus anacardium at dose of 200mg/kg the animal was shows significant effect (P>0.001) in 38 ±4.0510 sec. compared with negative control (18 ±2.5402 sec.). The gaseous messenger molecule nitric oxide (NO) is synthesized from its precursor L-arginine by a family of three NO Synthases (NOS), designated as â€Å"neuronal† NOS-I, â€Å"inducible† NOS-II and â€Å"endothelial† NOS-III. In the adult brain, the inducible iso form NOS-II is present only at very low levels in microglia and immune cells, while â€Å"endothelial† NOS-III is expressed predominantly in the vasculature. Whether or not this isoform is also expressed in neural cells, is still a matter of debate but data arguing for this are only sparse. The quantitatively major source for NO in the CNS thus is the â€Å"neuronal† isoform NOS-I present in approximately 1% of all neurons. Nitrinergic transmission is especially important in limbic structures, in the basal ganglia where NO regulates striatal output and in the cerebellum. NO exerts multiple action in the CNS and from animal studies, it has been suggested that it is involved in behavioral p rocesses such as learning and memory formation. Pathologies of the NO pathway have been implicated in almost every major neuropsychiatric disorder including Schizophrenia, affective disorders, Alcoholism, Alzheimer’s dementia, Parkinson and Huntington’s disease. For some of these disorders, NOS-I has also been identified as a risk gene in human case-control association studies. The role of NO in the regulation of normal human brain functioning however is still unclear, although first genetic studies argue for a function of NOS-I in the regulation of impulsive behaviors. In a second series of experiments, we investigated whether NOS-I knockdown animals have cognitive deficits. Plasma nitrates level was significantly decreased (P>0.001) after administration of Semecarpus anacardium at dose of 200 mg/kg (52.23 ±2.1401sec.) as compared with negative control (74.24 ±2.2406). In fear or anxiety, animal were showed increased level of plasma nitrates which was shows in negative control. iNOS level was significantly increased (P>0.001) after administration of Semecarpus anacardium at dose of 200mg/kg (78.37 ±3.2131sec.) as compared with negative control (26.23 ±2.5470 sec.). In addition to its role in cholinergic transmission, substantial evidence has accumulated over the last two decades which suggests a non- cholinergic neuromodulatory function for AChE. Few studies have demonstrated that the expression of AChE during early development correlate closely with the major phase of neurite outgrowth. Layer et al. have showed that AChE inhibitors have been shown to retard neuritic outgrowth in a dose dependent manner in retinal ganglion cells, dorsal root ganglion and sympathetic ganglion neurons. There is a growing body of evidence supporting the morphogenic effects of AChE in both in vivo and in vitro systems. AChE is known to regulate the neuritic outgrowth and survival of cultured neurons and also has morphogenic and axogenic role in the developing nervous system. In addition, AChE has a role in cell growth and survival. These functions are considered to be the non-classical roles of this classical enzyme. Furthermore, ACh is also known to enhance the ne uritic outgrowth and in turning of the nerve growth cones. These studies, together with the present demonstration of increased dendritic arborization in the hippocampus, suggest that chronic drug administration induces AChE activity which in turn might modulate dendritic branching pattern in specific brain regions. Ach level was significantly decreased (P>0.001) after administration of Semecarpus anacardium at dose of 200mg/kg (53.26 ±2.0987 sec.) as compared with negative control (81.23 ±3.0245 sec.). The efficacy of this plant extract toward the transmitters was significant. MAO regulates metabolic degradation of catecholamine, serotonin and other endogenous amines in CNS. Inhibition of this enzyme causes reduction of metabolism of these transmitters and subsequent increase of these biogenic amines. MAO-A level was significantly decreased (P>0.001) after administration of Semecarpus anacardium at dose of 200mg/kg (56.6 ±3.3245 sec.) as compared with negative control (86.1 ±2.3024 sec.). MAO-B level was significantly decreased (P>0.001) after administration of Semecarpus anacardium at dose of 200 mg/kg (44.8 ±3.2431 sec.) as compared with negative control (73.4 ±2.2061 sec.). Glutathione reductase level was significantly decreased (P>0.001) after administration of Semecarpus anacardium at dose of 200mg/kg (1478.5 ±3.2436 sec.) as compared with negative control (1634 ±2.2102 sec.). All values are expressed in U/I. Glutathione reductase level was decreased after administration of extract of Semecarpus anacardium at dose 200 mg/kg in mice. Glutathione reductase is the enzyme which increases in anxiety and depression. This enzyme secretes from hippocampus region of brain. The level of this enzyme was significantly reduced in mice compared with vehicle treated control group. On the bases of behavioral as well as biochemical estimation, study concludes that Semecarpus anacardium shows significant effect in plasma nitrates and other chemical messenger in anxiety at dose of 200mg/kg compared with negative control. 9. SUMMARY AND CONCLUSION The present study is designed to evaluate â€Å"Effect of Semecarpus anacardium on plasma nitrates on stress induced anxiety in mice†. Behavioral parameters show following result: After administration of Semecarpus anacardium Time spent in open arm in Elevated Plus Maze, Time cycle per five minute in Force Swim Test, Time spent in light area in Light and Dark Test, No. of Squire Cross in Open Field Test was significantly increased after administration of Semecarpus anacardium at dose of 200 mg/kg as compared with negative control. Biochemical Estimations show following result: Plasma nitrates level, Ach level, MAO-A level, MAO-B level, Glutathione reductase level was significantly decreased after administration of Semecarpus anacardium at dose of 200 mg/kg as compared with negative control. iNOS level was significantly increased after administration of Semecarpus anacardium at dose of 200mg/kg as compared with negative control. On the bases of behavioral as well as biochemical estimation, study concludes that Semecarpus anacardium shows significant effect in plasma nitrates and other chemical messenger in anxiety at dose of 200mg/kg compared with negative control. 6. Materials Methods 6.1 Materials Collection Authentication The plant Semecarpus anacardium has been taken from local market authenticated from Department of Botany Dr. H.S. Gour University, Sagar M.P. Herbarium No. Bot./her/A/1124. Extraction procedure 6.3.1 Petroleum ether extract: The whole plant nuts was cleaned and shaded dried for 10-15 days. The dried nuts were pulverized by an electrical blender and nut paste obtained. About 30-40 g of the nut paste was subject for extraction with 400 ml of Petroleum ether solvent by Soxhlet apparatus for 24 hrs. Constant heats of 50 60 0C provided by Mantox heater of Soxhlet for recycling the solvent. The extract was concentrate using Rotary evaporator at 60 0C for 20 min at a speed of 5m/s. The concentrated extract kept in refrigerator at 4 0C for further use. (50) 6.3.2 Ethanol extract: The nuts were shed dried for about 20 days and then subsequent to reduce coarse drug particle into fine powder using pestle and mortar. The extraction was carrying out by ethanol solvent Soxhlet extraction techniques. Solvent used consecutively with gradient polarity. The extract evaporated to complete dryness by using vacuum distillation and kept in refrigerator for further use. (51) Phytochemical screening 6.4.1 Tests for Alkaloids Mayer’s Test: Extract treated with Mayer’s reagent (Potassium Mercuric Iodide). Formation of a yellow coloured precipitate indicated the presence of alkaloids. Wagner’s Test: Extract treated with Wagner’s reagent (Iodine in Potassium Iodide). Formation of brown/reddish precipitate indicated the presence of alkaloids. Dragendroff’s Test: Extract treated with Dragendroff’s reagent (solution of Potassium Bismuth Iodide). Formation of red precipitate indicated the presence of alkaloids. Hager’s Test: Extract treated with Hager’s reagent (saturated picric acid solution). Presence of alkaloids confirm by the formation of yellow coloured precipitate. Tannic acid test: Extract treated with 10% Tannic acid solution. Alkaloids gave buff colour precipitate. (52) 6.4.2 Detection of Phenols Bromine water test: Test solution treated with few milliliters of bromine water. Formation of yellow precipitate indicated presence of Phenols. Ferric chloride test: Test solution gave blue green colour with ferric chloride. (53) 6.4.3 Detection of Saponins Emulsion test: 1 ml of the extract filtrate added to few drops of olive oil. The mixture added to another two drops of olive. The mixture shakes and observed for the formation of emulsion. Frothing test: 1 ml of the extract filtrate diluted with 4 ml of distilled water. The mixture was shake vigorously and then observed on standing for a stable froth. 6.4.4 Detection Steroids and Triterepenoids Libermann- Buchard test: Extract treated with few drops of acetic anhydride, boil and cool, conc. Sulphuric acid added from the sides of the test tube. Formation of a brown ring at the junction of two layers and the upper layer turns green which shows the presence of Steroids and formation of deep red colour indicated the presence of Triterepenoids. Salkowski test: Treated extract in Chloroform with few drops of cone. Sulphuric acid, shaked well and allowed standing for some time, red colour appeared at the lower layer indicates the presence of Steroids and formation of yellow coloured lower layer indicated the presence of Triterepenoids. 6.4.5 Detection of Tannins Lead sub-acetate test: 1 ml of the filtrate added to 3 drops of the lead sub-acetate solution. A cream gelatinous precipitate indicated the presence of tannins. Ferric chloride test: 1 ml of the filtrate diluted with distilled water and added with 2 drops of ferric chloride. A transient greenish to black colour indicated the presence of tannins. 6.4.6 Detection of Flavonoids Shinoda test (Magnesium Hydrochloride reduction test): To the test Solution, added few fragments of Magnesium ribbon and added concentrate Hydrochloric acid drop wise, pink scarlet, crimson red or occasionally green to blue colour appeared after few minutes. Alkaline reagent test: To the test solution added few drops of sodium hydroxide solution; formation of an intense yellow colour, which turned to Colourless on addition of few drops of dil. acid, indicated presence of Flavonoids. Ammonium test: A quantity (4 ml) each of the filtrates was shaking with 1 ml of dilute ammonia solution (1%). The layers allowed to separating. A yellow coloration at the ammonia layer indicates the presence of Flavonoids. Aluminium chloride test: A quantity (4 ml) each of the filtrates was shake with 1 ml of 1% aluminium chloride solution and observed for light yellow coloration. A yellow precipitate indicated the presence of Flavonoids. 6.4.7 Detection of Anthraquinones 1. Dilute sulphuric acid (5 ml) added to 0.1 g of the test extract in a test tube and boil for 15 min in a water bath. It was then cool and neutralize with 20% potassium hydroxide solution. A mixture, 10 ml of equal parts of Fehling’s solution A and B will add and boil for 5 min. A more dense red precipitate indicated the presence of glycoside. 2. About 0.5 ml of extract taken and subject to the following tests.1 ml of glacial acetic acid containing traces of ferric chloride and 1ml of concentrate sulphuric acid added to the extract and observed for the formation of the reddish brown colouration at the junction of two layers and the upper layer turned bluish green showed presence of Glycosides. Pharmacological Screening 6.5.1 Animal: Mice required as Animal model Body weight: 25 gms. Floor area per animal: 15 in2. Cage height: 5 inch. Temperature: 64 ° to 79 °F (18 ° to 26 °C). Relative Humidity: 40% to 70%. Number of air changes per hour: 10 – 15. Light levels: 30 foot-candles. Duration of Light: 12 -14 hours. Duration of Darkness: 10 12 hours. 6.5.3 Biochemical Estimation 6.5.3.1 Plasma Nitrate estimation: Plasma nitrate were measured by spectrophotomeric assay based on Griess reaction. Blood were withdrawn from tail vein of mice and plasma were using cooling centrifuge at 2500 rpm for 10 min. Plasma were mixed with equal volumes of Griess reagent (1% Sulphanilamide+ 0.1% naphthylelediamine dihydrochloride+ 2.5 % phosphoric acid) and incubated at room temp for 10 min. to yield a chromophore. Absorbance was read at 543 nm spectophotometrically.(59) 6.5.3.2 i NOS estimation: Sample collection After the behavioral tests, three mice from each group was deeply anesthetized and perfuse with 4% paraformaldehyde for subsequent Nissl staining. The other animals were anesthetized and kill; blood was collected and brains were removed. Blood, anticoagulated with 1.5% EDTA centrifuged at 12,000 rpm for 10 minutes, and then the supernatant was collected. All these samples stored at −80 °C for further analysis. RNA extraction and reverse transcription Total RNA extracted from the brain tissue using Trizol reagent. Total mRNA (1 ÃŽ ¼g) was transcribed using Quant script cDNA RT Kits according to the manufacturer’s manual. Briefly, RNA (1 ÃŽ ¼g) pretreated with DNA-free DNase treatment and removal reagents. RNA samples incubated with a mixture consisting of containing dNTPs, random primers, 10Ãâ€" RT mix, Quant Reverse Transcriptase, a reverse transcriptase and RNase-free water to a final volume of 10 ÃŽ ¼l at 37 °C for 1 h. Real-time RT-PCR cDNA l used for quantification of mRNA by real-time RT-PCR. Real-time RT-PCR will perform on an Applied Rotor-Gene 3000 under the following conditions: iNOS and GAPDH for 40 cycles at 94 °C for 30 s, 63 °C for 60 s, and 72 °C for 90 s. Relative quantitative measurements of target gene levels was performed using the ΔCt method, where Ct is the threshold concentration. GAPDH used as endogenous control to normalize gene expression data, and an RQ value calculated for each sample. RQ values was presented as fold change in gene expression relative to the control group, which normalized to 1. (60) The activity was expressed as m moles hydrolyzed per min per gram of tissue. AChE activity was statistically analyzed by Student’s Statistical analysis The statistical analysis carried out as per standard method. All result expressed as MEAN ±SEM. Groups of data were compared with the analysis of variance (ANOVA) followed by dunnett’s t-test values for statistical significance. Sagar Institute of Pharmaceutical Sciences, Sagar M.P. Page 1

Friday, January 17, 2020

Machiavelli’s Premise Essay

1. Do you agree with Machiavelli’s premise that if given the choice between the two, the prince is better served by being feared than loved? How does Machiavelli make the case for his position (details, modes)? Are his arguments convincing? If you took the self-analysis on high-Mach or low-Mach, what were the results, and were you surprised by your score? 2. What is the thesis of Neil Postman’s forward? Do you agree or disagree with his point of view? Provide support for your position. 1- The prince is better feared than loved, although striking a balance between the two would be best. As Machiavelli stated that the prince should do his utmost to escape hatred and too much fear would create hatred. The prince should try to balance love and fear based on his people and the situation at hand. 2- Both authors have different point of views; Orwell’s view is that we will be deprived of things by externally imposed oppression and by inflicting pain while Huxley’s view is that we will be distracted from our real goals with lust and pleasure. I agree to some extent on both points of views, except for the part that states that what we hate will ruin us. If you hate something that is bad then I don’t see anything wrong with it; I don’t think it can ruin us in any way. On the other hand I agree that lust and desire only lead to greed and other sins which corrupt us. Would time traveling be cool? Time travelling would not be cool. In fact many scientists have done a lot of research on black holes and time warps. Einstein did work on it as well as Stephen Sawking to no avail. Actually Stephen changed his theory on the black holes losing and retaining information twice. If time traveling was possible we would be open to endless opportunities and nothing would be a challenge. Life would be stale without surprises, discoveries and evolution.

Thursday, January 9, 2020

Bauhaus Influences on Photography and Architecture

History of Photography Final Research Project Bauhaus: Influences on Photography and Architecture After the defeat in the First World War and the fall of the German monarchy, Germany faced darkness and lost hope in the future. Walter Gropius, a German architect, who served in the war, saw the need of re-orienting the art world for the better (Westphal, 7). One year after the First World War, 1919, Gropius opened a school in Weimar, Germany called the Bauhaus school. His intention for this school was to create a total work of art in which all arts would be brought together (Bayer, 12). He also wanted to create a â€Å"consulting art center for industry and the trades† (Bayer, 13). In his Bauhaus Manifesto, Gropius mentions†¦show more content†¦Some of his assignments were to create an impression of three-dimensionality in a two-dimensional drawing, and figurative studies drawing from nature (Westphal, 51). Wassily Kandinsky taught analytical thought process to help students understand the basic concepts of design in painting. His class included learning color, shapes, lines, composition, and characteristics (Westphal, 54). Paul Klee taught the analysis of sensory perception, picture construction, and color theory on a more intense level (Westphal, 59). He mentions that Expressionism, the strength to discover the inner strength, and science played a huge role in his curriculum (Westphal, 59). Oskar Schlemmer taught stage and costume design (Westphal, 60). After the preliminary courses, students would have the opportunity to eight workshops: furniture, metal, print and advertizing, photography, theatre, wall painting, ceramics, and weaving (Westphal, 73). These courses prepared students to acquire solid craft skills. Also, just like the preliminary courses, the workshop would be an in-depth learning and experience of each subject. The photography department was under Walter Peterhans in 1929. Photography was initially only used for catalogue illustrations for advertising (Moholy-Nagy, 134). With Moholy-Nagy’ s enthusiasm in photography, he was able to bring respect to the Bauhaus school. Moholy-Nagy also suggested the termShow MoreRelatedMoholy-Nagy and the Bauhaus1009 Words   |  5 PagesLaszlo Moholy-Nagy and The Bauhaus Laszlo Moholy-Nagy was a Hungarian constructivist who was gifted in most forms of the visual arts. He was born in 1895 and raised in the city of Bachsbarsad, Hungary and studied law in Hungarys capital of Budapest. He began his artistc venture during his service in World War I with sketches on military-issue postcards, and produced a versatile catalog of works throughout his life. He was skilled in design, sculpture, painting, photography, and more. He was alsoRead MoreThe Bauhaus : Art Education By Influencing Graphic, Interior, And Typography Design1096 Words   |  5 PagesThe Bauhaus affected art education by influencing graphic, interior, and typography design. It is said that it inspired the rise of many other art schools. In this paper there will be specific information discussed to help each reader in understanding the history of the Bauhaus. Let’s start with a little bit of the back-story of the Bauhaus and its founder Walter Gropius. In 1919 the Bauhaus, a Germa n word meaning house of building, was a school founded in Weimar, Germany by architect WalterRead MoreContemporary Artists : Art No Authority Can Tell Your Own Body With A Knife1733 Words   |  7 Pageswish I had half as much creative talent as the artists who draw for comics. Another large influence of contemporary design is Grunge Style. This style was very anti-establishment, which is obvious in the magazine Ray Gun and the artwork created by the firm Tomato. Grunge style of course is not the only big contributor to the contemporary style; every movement that has happened in design history influences all artists today. There is a video that says everything is a remix, and I believe that toRead MoreGraphic Design Of A Graphic Designer Essay1870 Words   |  8 PagesSchmidt have both used these techniques to produce astonishing pieces of graphic design, which are going to be compared and contrasted throughout this essay. The 1923 legendary typographer and graphic designer Joost Schmidt in Weimar, Germany created Bauhaus Exhibition Poster. The other piece of design I have decided to analyse is a two-page spread of the edition of works of Geoffrey Chaucer. This was the Kelmscott press finest achievement; it was designed by William Morris and illustrated by his friendRead MoreModernism, Modernity and Modernisation: Urban Growth in Melbourne Between the Wars1533 Words   |  7 Pagesâ€Å"It was a conviction that what mans eye seeks in our era, in our time, is not the ponderous solidity of traditional architecture where everything was built to four walls around a room and spaces that were finite. But rather our eyes seek transparency, lightness... being able to look through things.† (http://australia.gov.au/about-australia/australian-story/modern-austn-architecture) Although Seidler’s designs flourished after World War Two, his works utilised the new materials, technology and machineryRead MoreEssay about Summary of History of Graphic Design by Meggs14945 Words   |  60 Pagesof newborn calves (LOL). - The codex replaced the scroll, as it consisted of stacked pieces of paper much like a modern book. - Graphic symbols became a representation of religious belief during the Roman Empire. - Rome’s legacy includes architecture, engineering, language, law and literature. - Just as the invention of printing launched a quiet revolution in Chinese culture, alphabetic writing on papyrus slowly transformed Western society. - Alphabetic writing was spread by armies, tradersRead MoreIwc1 Literature, Arts and Humanities Essay10028 Words   |  41 Pagesgeneral conclusion (or from effect to cause). Question 5: Multiple Choice Why is architecture considered an art? a) Because architecture provides shelter to humans b) Because architecture is often decorated with art forms c) Because architects use perspective in their work d) Because architecture is concerned with the aesthetic effect of structures in their environment Feedback: The correct answer is d. Architecture is considered an art because it is concerned with the aesthetic effect of structuresRead MoreModernism, Modernisation and Modernity in Australia, 1919 –19391907 Words   |  8 Pages–1939 Lighting the Way: New technologies, new materials, new cities. Modernism transformed life in Australia across five tumultuous decades from 1917 to 1967 , it spans all aspect of Australian culture including art, design, architecture, advertising, film, photography and fashion. The process of modernisation has had a profound affect, changing our perspectives and the course of our everyday living. Change is inevitable, man-made environments are changing all the time, people are gettingRead More The Russian Avant Garde and the Bolshevik Revolution Essay1939 Words   |  8 PagesAfter the October Revolution both Tatlin and Malevich opened up art schools. Malevich’s Suprematist school was similar in style but not ideology to the De Stijl movement in Holland, while the Constructivist school of Tatlin’s had links to the German Bauhaus. The October revolution had been a primarily proletariat revolution and proletarians have proven to be somewhat negative in their attitude to new, radical confronting art styles and this was no exception. Both schools realised they had to prove theirRead MoreChapter 33 – Early 20th Century5648 Words   |  23 Pages | |d. |Frida Kahlo | ____ 17. Which of the following artists shared Stieglitzs concern to position photography as an art form with the same fine-art status as painting and sculpture? |a. |Dorothea Lange | |b. |Georgia OKeeffe

Wednesday, January 1, 2020

Names and Dates of Spartan Kings

The ancient Greek city of Sparta was ruled by two kings, one from each of the two founding families, Agaidai and Eurypontidae. Spartan kings inherited their  roles, a job filled by the leader of each family. Although not much is known about the kings — note how few of the kings listed below even have regnal dates — ancient historians have pieced together general information about how the government worked. Spartan Monarchical Structure Sparta was a constitutional monarchy, made up of the kings, advised by and (supposedly) controlled by a college of ephors; a council of elders called the Gerousia; and an assembly, known as the Apella or Ecclesia. There were five ephors who were elected annually and swore fealty to Sparta rather than the kings. They were there to  call up the army and receive foreign envoys. The Gerousia was a council made up of men who were over the age of 60; they made decisions in criminal cases. The Ecclesia was made up of every Spartan male full citizen who had attained his 30th birthday; it was led by the ephors and they  supposedly made decisions on when to go to war and who would be the commander in chief.   Dual Kings   Having two kings share power was fairly common in several Bronze Age Indo-European societies; they shared power but had different roles. Like Mycenaean kings in Greece, the Spartans had a political leader (the Eurypontidae kings) and a war leader (the Agaidai kings). Priests were people outside of the regnal pair and neither of the kings was considered sacred — although they could enable contact with the gods, they were never interpreters. They were involved in certain religious or cultic activities, members of the priesthood of Zeus Lacedaemon (a cult group based honoring the mythical king of Laconia) and Zeus Ouranos (Uranus, the primal sky god).   The Spartan kings werent believed to be supernaturally strong or sacred, either. Their role in Spartan life was shouldering certain magisterial and juridical responsibilities. Although this made them relatively weak kings and there was always input from the other pieces of the government on most of the decisions they made, most of the kings were fierce and acted independently most of the time. Remarkable examples of this include the famed first  Leonidas  (ruled 490–480 BCE for the house of Agaidai), who traced his ancestry to Hercules and was featured in the movie 300. Names Dates of the Kings of Sparta House of Agaidai House of Eurypontidai Agis 1 Echestratos Eurypon Leobotas Prytanis Dorrusas Polydectes Agesilaus I Eunomos Archilaus Charillos Teleklos Nikandros Alkamenes Theopompos Polydoros Anaxandridas I Eurykrates Archidamos I Anaxandros Anaxilas Eurykratidas Leotychidas Leon 590-560 Hippocratides 600–575 Anaxandrides II 560–520 Agasicles 575–550 Cleomenes 520–490 Ariston 550–515 Leonidas 490–480 Demaratus 515–491 Pleistrachus 480–459 Leotychides II 491–469 Pausanias 409–395 Agis II 427–399 Agesipolis I 395–380 Agesilaus 399–360 Cleombrotos 380–371 Agesipolis II 371–370 Cleomenes II 370–309 Archidamos II 360–338 Agis III 338–331 Eudamidas I 331– ? Araios I 309–265 Archidamos IV Akrotatos 265–255? Eudamidas II Araios II 255/4–247? Agis IV ?–243 Leonidas 247?–244;243–235 Archidamos V ?–227 Kleombrotos 244–243 [interregnum] 227–219 Kleomenes III 235–219 Lykurgos 219– ? Agesipolis 219– Pelops(Machanidas regent) ?–207 Pelops(Nabis regent) 207–? Nabis ?–192 Sources Chronology of Monarchical Rule (from the now-defunct Herodotus website)Adams, John P. â€Å"The kings of Sparta.†Ã‚  California State University, Northridge.  Ã‚  Lyle, Emily B. Dumezils Three Functions and Indo-European Cosmic Structure. History of Religions 22.1 (1982): 25-44. Print.Miller, Dean A. The Spartan Kingship: Some Extended Notes on Complex Duality. Arethusa 31.1 (1998): 1-17. Print.Parke, H. W. The Deposing of Spartan Kings. The Classical Quarterly 39.3/4 (1945): 106-12. Print.Thomas, C. G. On the Role of the Spartan Kings. Historia: Zeitschrift fà ¼r Alte Geschichte 23.3 (1974): 257-70. Print.